GeneProof Human Papillomavirus (HPV) Screening PCR Kit

GeneProof Human Papillomavirus (HPV) Screening PCR Kit has expanded compatibility! 

The assay is now validated for use with BD SurePath^TM Preservative Fluid and PreservCyt^TM Solution (Hologic), along with other transport media and self-sampling devices. 

PRODUCT ADVANTAGES

DIFFERENTIATION OF HIGH-RISK TYPES 16, 18 AND 45

• The kit detects a pool of high-risk HPV types with differentiation of types 16, 18 and 45 
• HPV16 and HPV18 are responsible for 70 % of cervical cancer cases and pre-cancerous cervical lesions, while HPV45 is the 3rd most prevalent genotype in cases of invasive cervical cancer worldwide (5–6%) ^(1), (2)

TRANSPORT MEDIA COMPATIBILITY

• With the most commonly used transport media validated, the assay is easy to adopt into your laboratory's existing workflow 

• Validated for use with:  

  • PreservCyt^TM Solution (Hologic) 

  • BD SurePath^TM Preservative Fluid 

  • NOVAPrep^® Solution (Novacyte) 

SELF-SAMPLING OPTION

• Compatible with devices for simple and convenient self-sampling

• Validated for use with: 

  • Evalyn^® Brush (Rovers Medical) 

  • FLOQSwab^® (COPAN) 

• Proper sampling can be assessed through the endogenous internal control (GADPH gene)

CONTAMINATION PREVENTION

• Ready-to-Use Master Mix contains Uracil-DNA glycosylase (UNG) and dUTPs eliminating possible carryover contamination

COMPATIBLE WITH A WIDE RANGE OF REAL-TIME PCR DEVICES

CE IVD CERTIFIED DIAGNOSTIC TEST

⁽¹⁾ Wang R, Pan W, Jin L, Huang W, Li Y, Wu D, Gao C, Ma D, Liao S. Human papillomavirus vaccine against cervical cancer: Opportunity and challenge. In: Cancer Letters [Internet]. Amsterdam (NL): Elsevier; 2020 Feb 28;471:88-102. Available from: [https://doi.org/10.1016/j.canlet.2019.11.039].

⁽²⁾ Andrews J. HPV45: Why does it matter? Clinical utility in risk-stratified cervical cancer screening & management: systematic review. In: ASSCP 2018 Annual Meeting [Internet]. Sparks (MD): BD Life Sciences; 2018. Available from: [https://www.asccp.org/Assets/3e568d4b-5fb4-4e82-9c5b-ee648207a56a/636603484014070000/1140-jeff-andrews-pdf]